CD11c Antibody / ITGAX

• Catalog Number: orb749365
• Category: Antibodies
• Description: CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: HC1/1
• Tested applications: FACS, Functional Studies, IF
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.
• Dilution range: Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml,Functional studies (order BSA/sodium azide-free format)
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This CD11c antibody is available for research use only.
• Entrez: 3687
• Storage: Store the CD1°C antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.
• Expiration Date: 12 months from date of receipt.

FACS staining of human PBMCs using CD11c antibody (HC1/1).