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Catalog Number | orb1952605 |
---|---|
Category | Antibodies |
Description | CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration. |
Clonality | Monoclonal |
Clone Number | CBR-IC2/2 |
Tested applications | FC |
Reactivity | Human |
Isotype | Mouse IgG2a |
Immunogen | Human CD102 cDNA transfected COS cells |
Conjugation | FITC |
Target | CD102 |
Entrez | 3384 |
UniProt ID | P13598 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | ICAM2 Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
Separation of human monocytes (red-filled) from CD102 negative neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD102 (CBR-IC2/2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD102 (CBR-IC2/2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).
Mouse | |
Monoclonal | |
FITC |
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