CCT128930 hydrochloride

• Catalog Number: orb1300887
• Category: Small Molecules
• Description: CCT128930 hydrochloride
• CAS Number: 2453324-32-6
• Purity: 98.55%
• MW: 378.3
• SMILES: NC1(CC2=CC=C(Cl)C=C2)CCN(C3=C4C(NC=C4)=NC=N3)CC1.[H]Cl
• Formula: C₁₈H₂₁Cl₂N₅
• Biological Activity: CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50: 168 nM) through the targeting of Met282 of AKT, as well as 20-fold selectivity over p70S6K (IC50: 120 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.