CCR7 antibody

• Catalog Number: orb758968
• Category: Antibodies
• Description: Rabbit monoclonal antibody to CCR7
• Species/Host: Rat
• Clonality: Monoclonal
• Clone Number: 4B12
• Tested applications: FA, FC, IP
• Reactivity: Mouse
• Isotype: IgG
• Immunogen: This antibody was raised by immunizing rats with mouse CCR7 antigen.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: CCR7
• UniProt ID: P47774
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: EBI1; EBV-induced G-protein coupled receptor 1; Ep
• Note: For research use only
• Application notes: This antibody was used for flow cytometry and the staining quality can be improved by incubation at 37°C (Britschgi et al, 2008). This antibody is widely used to monitor the activation of dendritic cells in mice (Ohl et al, 2004; Ritter et al, 2004; Zhao et al, 2019). It was also utilized in immunoprecipitation of the CCR7 receptor protein (Ritter et al, 2004). The antibody does not interfere with ligands binding to the CCR7 receptor, which was confirmed by a transmigration assay (Ritter et al, 2004). It does not interfere with T-cell migration (Ritter et al, 2004). The antibody also is not agonistic as it does not activate the receptor (Ritter et al, 2004).
• Expiration Date: 12 months from date of receipt.