CCG-50014

• Catalog Number: orb611533
• Category: Small Molecules
• Description: CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is > 20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.
• CAS Number: [883050-24-6]
• MW: 316.35
• SMILES: FC1C=CC(CN2C(=O)SN(C3C=CC(C)=CC=3)C2=O)=CC=1
• Formula: C₁₆H₁₃FN₂O₂S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.