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Catalog Number | orb692137 |
---|---|
Category | Small Molecules |
Description | CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells. |
CAS Number | [61034-15-9] |
MW | 271.28 |
SMILES | N1C2=C(N(C)C(=O)N(C)C2=O)N=C1NC1=CC=CC=C1 |
Formula | C13H13N5O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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