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Catalog Number | orb1303815 |
---|---|
Category | Small Molecules |
Description | CAY10781 |
CAS Number | 1210360-87-4 |
Purity | 98.69% |
MW | 231.21 |
SMILES | OC(=O)Cc1cnc([nH]c1=O)-c1cccnc1 |
Formula | C11H9N3O3 |
Biological Activity | CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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