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Catalog Number | orb180468 |
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Category | Antibodies |
Description | Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. |
Species/Host | Goat |
Clonality | Polyclonal |
Tested applications | IEM, IF, IHC-Fr, IHC-P, WB |
Reactivity | Bovine, Canine, Donkey, Equine, Feline, Gallus, Goat, Guinea pig, Hamster, Human, Mouse, Other, Porcine, Primate, Rabbit, Rat, Sheep |
Isotype | IgG |
Immunogen | Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli. |
Concentration | 3 mg/ml |
Dilution range | WB:1:250-1:1,000, IF:1:50-1:200, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000, IEM:1:50-1:200 |
Form/Appearance | Polyclonal antibody supplied as a 200 or 500 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum. |
Conjugation | Unconjugated |
Target | Cathepsin D |
Storage | Store at -20°C for long-term storage. Store at 2-8°C for up to one month. |
Buffer/Preservatives | PBS, 20% glycerol and 0.05% sodium azide |
Alternative names | ceroid-lipofuscinosis, CLN10; CPSD, CTSD, lysosoma Read more... |
Note | For research use only |
Application notes | The antibody solution should be gently mixed before use. |
Expiration Date | 12 months from date of receipt. |
Feng, Xu et al. Genome-wide differential expression profiling of mRNAs and lncRNAs associated with prolificacy in Hu sheep Biosci Rep, 38, (2018)
Western blot analysis of CTSD and 293FT cell line lysate using Cathepsin D antibody.
Immunohistochemical analysis of formalin-fixed paraffin embedded mouse lung tissue using Cathepsin D antibody.
Immunohistochemical analysis of Cathepsin D antibody
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