Caspase 8 (Phospho-Ser347) antibody

• Catalog Number: orb106251
• Category: Antibodies
• Description: Rabbit polyclonal to Caspase 8 (Phospho-Ser347). This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IHC-P, WB
• Reactivity: Human, Rat
• Dilution range: WB:1:500-1:2000, IHC-P:1:50-1:200
• Conjugation: Unconjugated
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti Apoptotic cysteine protease antibody, anti Ap
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of Jurkat whole cell lysates using Caspase 8 (Phospho-Ser347) antibody, The lane on the left is treated with the antigen-specific peptide.