CAMK2G antibody

• Catalog Number: orb153758
• Category: Antibodies
• Description: Rabbit polyclonal antibody to CAMK2G. CaMKII is an important member of the calcium/calmodulinactivated protein kinase family, functioning in neural synaptic stimulation and T cell receptor signaling (1,2). CaMKII has catalytic and regulatory domains. Ca2+/calmodulin binding to the CaMKII regulatory domain relieves autoinhibition and activates the kinase (3). The activated CaMKII further autophosphorylates at Thr286 to render the kinase constitutively active (3). The threonine phosphorylation state of CaMKII can be regulated through PP1/PKA. PP1 (protein phosphatase 1) dephosphorylates phosphoCaMKII at Thr286. PKA (protein kinase A) prevents phosphoCaMKII (Thr286) dephosphorylation through an inhibitory effect on PP1.
• Clonality: Polyclonal
• Tested applications: ICC, IF, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG
• Immunogen: Recombinant fusion protein of human CAMK2G(NP_751909.1).
• Dilution range: WB: 1:500-2000, IHC-P: 1:50-200
• Conjugation: Unconjugated
• MW: 75kDa/80kDa
• UniProt ID: Q13555
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Alternative names: anti CAMK antibody, anti CAMKII antibody, anti CAM
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of extracts of various cells using CAMK2G antibody

Immunohistochemical staining of human gastric tissue using CAMK2G antibody (dilution of 1:100)

Immunohistochemical staining of rat heart tissue using CAMK2G antibody (dilution of 1:100)

Immunohistochemical staining of mouse heart tissue using CAMK2G antibody (dilution of 1:100)