Calmidazolium chloride

• Catalog Number: orb1309880
• Category: Small Molecules
• Description: Calmidazolium chloride
• CAS Number: 57265-65-3
• Purity: 98.06%
• MW: 687.7
• SMILES: ClC1=CC=C(COC(C2=CC=C(Cl)C=C2Cl)CN3C=[N+](C(C4=CC=C(Cl)C=C4)C5=CC=C(Cl)C=C5)C=C3)C(Cl)=C1.[Cl-]
• Formula: C₃₁H₂₃Cl₇N₂O
• Biological Activity: Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase(IC50 = 0.35 μM). Calmidazolium chloride also induces apoptosis in certain cancer cell lines.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.