Cabozantinib S-malate

• Catalog Number: orb342251
• Category: Small Molecules
• Description: Cabozantinib S-malate (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
• CAS Number: [1140909-48-3]
• MW: 635.593
• SMILES: O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O
• Formula: C₃₂H₃₀FN₃O₁₀
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Cabozantinib S-malate