Cabozantinib

• Catalog Number: orb1305297
• Category: Small Molecules
• Description: Cabozantinib
• CAS Number: 849217-68-1
• Purity: 99.88%
• MW: 501.51
• SMILES: O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC=4C=CN=C5C=C(OC)C(OC)=CC54)C=C3)CC2
• Formula: C₂₈H₂₄FN₃O₅
• Biological Activity: Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.