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Catalog Number | orb1302037 |
---|---|
Category | Small Molecules |
Description | Cabozantinib hydrochloride |
CAS Number | 1817759-42-4 |
Purity | 99.72% |
MW | 537.96 |
SMILES | Cl.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC |
Formula | C28H25ClFN3O5 |
Biological Activity | Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |