CA-4948

• Catalog Number: orb757679
• Category: Small Molecules
• Description: CA-4948 is a potent IRAK4/FLT3 inhibtor with anti-tumor activity[1].CA-4948 is over 500-fold more selective for IRAK-4 compared to IRAK-1. CA-4948 reduces TNF-α, IL-1β, IL-6 and IL-8 release from TLR-Stimulated THP-1 Cells with an IC50 < 250 nM. CA-4948 al
• CAS Number: [1801344-14-8]
• MW: 491.4992044
• SMILES: O([H])[C@@]1([H])C([H])([H])N(C2C(=C([H])C3=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])O3)N=2)N([H])C(C2=C([H])OC(C3C([H])=C([H])N=C(C([H])([H])[H])C=3[H])=N2)=O)C([H])([H])C1([H])[H]
• Formula: C₂₄H₂₅N₇O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.