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Catalog Number | orb1960764 |
---|---|
Category | Proteins |
Description | C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactive Protein /CRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.1 kDa and the accession number is P02741-1. |
Tag | N-His |
Purity | > 95% |
MW | 24.1 kDa (predicted). Due to glycosylation, the protein migrates to 25-27 kDa based on Tris-Bis PAGE result. |
UniProt ID | P02741 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactive Protein /CRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.1 kDa and the accession number is P02741-1. |
Expression Region | Gln19-Pro224 |
Storage | -20°C |
Note | For research use only |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expiration Date | 6 months from date of receipt. |
> 95% as determined by SDS-PAGE | |
27 kDa |
> 95% as determined by SDS-PAGE | |
25 kDa |
≥90% as determined by SDS-PAGE | |
This protein contains the human CRP(Gln19-Pro224) was fused with the C-terminal His Tag and expressed in E. coli. |