BTSA1.2

• Catalog Number: orb1146690
• Category: Small Molecules
• Description: BTSA1.2 is a rationalized BTSA1 analog with improved binding to BAX, cellular cytotoxicity, and better toleratence in vivo. Combination of BTSA1.2 with Navitoclax demonstrates synergistic efficacy in apoptosis-resistant cancer cells, xenografts, and patient-derived tumors while sparing healthy tissues.
• CAS Number: [2254256-66-9]
• MW: 458.56
• SMILES: O=C1N(N=C(C=2C=CC=CC2)C1N=NC3=NC(=C(S3)C)C)C4=NC(=CS4)C=5C=CC=CC5
• Formula: C₂₃H₁₈N₆OS₂
• Hazard Information: Non-Toxic
• Note: For research use only
• Expiration Date: 12 months from date of receipt.