BT-2

• Catalog Number: orb783554
• Category: Small Molecules
• Description: BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC)[1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM[2].
• CAS Number: [34576-94-8]
• MW: 247.09786
• SMILES: ClC1=CC2=C(C=C1)C(Cl)=C(C(O)=O)S2
• Formula: C₉H₄O₂SCL₂
• Hazard Information: Non-Toxic
• Note: For research use only
• Expiration Date: 12 months from date of receipt.