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Catalog Number | orb1305304 |
---|---|
Category | Small Molecules |
Description | Brivanib (alaninate) |
CAS Number | 649735-63-7 |
Purity | 99.23% |
MW | 441.46 |
SMILES | O(C=1C=2N(C=C(OC[C@H](OC([C@H](C)N)=O)C)C2C)N=CN1)C=3C(F)=C4C(=CC3)NC(C)=C4 |
Formula | C22H24FN5O4 |
Biological Activity | Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
649735-63-7 |
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