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Catalog Number | orb2281003 |
---|---|
Category | Small Molecules |
Description | Brivanib Alaninate-d4 is a deuterated compound of Brivanib Alaninate. Brivanib Alaninate has a CAS number of 649735-63-7. Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. |
Purity | 98.00% |
MW | 445.48 |
SMILES | CC1=CC2=C(F)C(OC3=NC=NN4C3=C(C)C(OC[C@@H](C)OC(C(N)([2H])C([2H])([2H])[2H])=O)=C4)=CC=C2N1 |
Formula | C22H20D4FN5O4 |
Biological Activity | Brivanib Alaninate-d4 is a deuterated compound of Brivanib Alaninate. Brivanib Alaninate has a CAS number of 649735-63-7. Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |