Brexpiprazole HCl

SKU: orb1298710

Description

Brexpiprazole hydrochloride, also known as OPC-34712 dihydrochloride, is a novel atypical antipsychotic compound used in research. It is applied in preclinical studies for investigating schizophrenia and depression, utilizing both in vitro receptor binding assays and in vivo behavioral models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 913612-38-1
• MW: 433.6
• Purity: ≥98%
• Formula: C₂₅H₂₇N₃O₂S.xHCl
• SMILES: Cl.O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1
• Target: Others,5-HT Receptor,Adrenergic Receptor,Dopamine Receptor
• Solubility: DMSO:27.5 mg/mL (63.42 mM)

Bioactivity

• Target IC50:
  noradrenergic α2C (human):0.59 nM (Ki)|5 hT1A receptor:0.12 nM (Ki)|5 hT2A receptor:0.47 nM (Ki)|D2L receptor:0.3 nM (Ki)|noradrenergic α1B (human):0.17 nM (Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

recognition deficits, Serotonin Receptor, Dopamine Receptor, Brexpiprazole HCl, Brexpiprazole, Beta Receptor, 5-hydroxytryptamine Receptor, 5-HT Receptor, Adrenergic Receptor, antipsychotic, neurite outgrowth, PC12, orally active, OPC34712, OPC-34712, OPC34712 Dihydrochloride, OPC-34712 Dihydrochloride, OPC 34712, OPC 34712 dihydrochloride, OPC 34712 Dihydrochloride, inhibit, Inhibitor

Compound Identifiers

PubChem CID

66884211