BRD6989

• Catalog Number: orb1308524
• Category: Small Molecules
• Description: BRD6989
• CAS Number: 642008-81-9
• Purity: 98.82%
• MW: 264.33
• SMILES: C(#N)C=1C(=C2C(=NC1N)CCC(C)C2)C=3C=CC=NC3
• Formula: C₁₆H₁₆N₄
• Biological Activity: BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.