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Catalog Number | orb1309904 |
---|---|
Category | Small Molecules |
Description | BRD0705 |
CAS Number | 2056261-41-5 |
Purity | 99.59% |
MW | 321.42 |
SMILES | C(C)[C@]1(C2=C(NC=3C1=CNN3)CC(C)(C)CC2=O)C4=CC=CC=C4 |
Formula | C20H23N3O |
Biological Activity | BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50: 515 nM). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98% | |
1597440-03-3 | |
321.42 | |
C20H23N3O |
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