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Catalog Number | orb1089880 |
---|---|
Category | Small Molecules |
Description | BRD-K98645985 is a class of 12-membered macrolactam and a BAF transcriptional repression inhibitor with an EC50 of ~2.37 μM. BRD-K98645985 binds ARID1A-specific BAF complexes, prevents nucleosomal positioning, and potently reverses HIV-1 latency, and without T cell activation or toxicity. |
CAS Number | [1357647-78-9] |
MW | 573.73 |
SMILES | O=C(NC1=CC=C(OC[C@H](C)N(CC2=CC=C(C3=NC=CC=C3)C=C2)C[C@H](C)[C@@H](OC)CN(C)C4=O)C4=C1)NC(C)C |
Formula | C33H43N5O4 |
Hazard Information | Non-Toxic |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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