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Catalog Number | orb1305542 |
---|---|
Category | Small Molecules |
Description | Bortezomib |
CAS Number | 179324-69-7 |
Purity | 99.91% |
MW | 384.24 |
SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@@H](CC(C)C)B(O)O)=O)NC(=O)C=2C=NC=CN2 |
Formula | C19H25BN4O4 |
Biological Activity | Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can disrupt the cell cycle and induce apoptosis. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[1047645-82-8] | |
463.7841 | |
C18H18CL3FN4OS |
[179324-69-7] | |
384.2372 | |
C19H25BN4O4 |
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