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Catalog Number | orb1305542 |
---|---|
Category | Small Molecules |
Description | Bortezomib |
CAS Number | 179324-69-7 |
Purity | 99.97% |
MW | 384.24 |
SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |
Formula | C19H25BN4O4 |
Biological Activity | Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can disrupt the cell cycle and induce apoptosis. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[179324-69-7] | |
384.2372 | |
C19H25BN4O4 |
[1047645-82-8] | |
463.7841 | |
C18H18CL3FN4OS |