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Catalog Number | orb1683056 |
---|---|
Category | Small Molecules |
Description | Boehmenan |
CAS Number | 57296-22-7 |
Purity | 98% |
MW | 712.74 |
SMILES | COc1cc(CCCOC(=O)\C=C\c2ccc(O)c(OC)c2)cc2[C@@H](COC(=O)\C=C\c3ccc(O)c(OC)c3)[C@@H](Oc12)c1ccc(O)c(OC)c1 |
Formula | C40H40O12 |
Biological Activity | (±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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