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BN82002 hydrochloride

BN82002 hydrochloride

Catalog Number: orb1691998

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Catalog Numberorb1691998
CategorySmall Molecules
DescriptionBN82002 hydrochloride
CAS Number1049740-43-3
Purity98%
MW395.88
SMILESCl.COc1cc(cc(CN(C)CCc2ccc(cc2)[N+]([O-])=O)c1O)N(C)C
FormulaC19H26ClN3O4
Biological ActivityBN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. Additionally, BN82002 hydrochloride exhibits approximately 20-fold greater selectivity over CD45 tyrosine phosphatase.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.