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Catalog Number | orb1691998 |
---|---|
Category | Small Molecules |
Description | BN82002 hydrochloride |
CAS Number | 1049740-43-3 |
Purity | 98% |
MW | 395.88 |
SMILES | Cl.COc1cc(cc(CN(C)CCc2ccc(cc2)[N+]([O-])=O)c1O)N(C)C |
Formula | C19H26ClN3O4 |
Biological Activity | BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. Additionally, BN82002 hydrochloride exhibits approximately 20-fold greater selectivity over CD45 tyrosine phosphatase. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |