BMX-IN-1

• Catalog Number: orb611765
• Category: Small Molecules
• Description: BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
• CAS Number: [1431525-23-3]
• MW: 524.5903
• SMILES: C=CC(NC1C(C)=CC=C(N2C(=O)C=CC3=C2C2=CC(C4=CC=C(NS(=O)(C)=O)C=C4)=CC=C2N=C3)C=1)=O
• Formula: C₂₉H₂₄N₄O₄S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.