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Catalog Number | orb1308543 |
---|---|
Category | Small Molecules |
Description | BMX-IN-1 |
CAS Number | 1431525-23-3 |
Purity | 98% |
MW | 524.59 |
SMILES | O=C1N(C2=C3C(=NC=C2C=C1)C=CC(=C3)C4=CC=C(NS(C)(=O)=O)C=C4)C5=CC(NC(C=C)=O)=C(C)C=C5 |
Formula | C29H24N4O4S |
Biological Activity | BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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