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Catalog Number | orb1744391 |
---|---|
Category | Small Molecules |
Description | BMS-986339 |
CAS Number | 2477873-64-4 |
MW | 643.71 |
SMILES | C(C)(C)(F)C1=NC(C23CCC(CN(C(=O)[C@H]4C[C@@](C(F)(F)F)(O)C4)C5=CC(=CC=C5)C6=CC=C(C(C)(C)O)C=C6)(CC2)CC3)=NO1 |
Formula | C35H41F4N3O4 |
Biological Activity | BMS-986339 is an orally active, potent FXR agonist that interacts via H-bond formation with the His298 and ASN287 residues. It is utilized in research focused on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) for its anti-fibrosis properties. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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