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Catalog Number | orb1300463 |
---|---|
Category | Small Molecules |
Description | BMS-911543 |
CAS Number | 1271022-90-2 |
Purity | 99.98% |
MW | 432.52 |
SMILES | CN1C=2C3=C(N(CC)C(C(N(C4CC4)C5CC5)=O)=C3)N=C(NC=6C=C(C)N(C)N6)C2N=C1 |
Formula | C23H28N8O |
Biological Activity | BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1271022-90-2 |
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