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Catalog Number | orb180855 |
---|---|
Category | Small Molecules |
Description | BMS 833923 is an orally bioavailable inhibitor of Smo. It blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM). BMS 833923 robustly inhi |
CAS Number | [1059734-66-5] |
MW | 473.57 |
SMILES | C(NC1=CC(CNC)=CC=C1C)(=O)C1=CC=C(NC2=NC(C3=CC=CC=C3)=C3C(=N2)C=CC=C3)C=C1 |
Formula | C30H27N5O |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of BMS-833923 (XL-139)