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BMS-599626 2HCL(714971-09-2 Free base)
Catalog Number: orb1737829
| Catalog Number | orb1737829 |
|---|---|
| Category | Small Molecules |
| Description | BMS-599626 2HCL(714971-09-2 Free base) |
| CAS Number | 1781932-33-9 |
| Purity | 0.9873 |
| MW | 603.47 |
| SMILES | O=C(OC[C@@H]1COCCN1)NC2=CN3C(C(NC4=CC=C(N(N=C5)CC6=CC(F)=CC=C6)C5=C4)=NC=N3)=C2C.Cl.Cl |
| Formula | C27H29Cl2FN8O3 |
| Biological Activity | BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative. BMS-599626 is an orally available and selective dual inhibitor of HER1 and HER2 with IC50s of 20 and 30 nM, respectively. BMS-599626 inhibits tumor cell proliferation and has the potential to increase tumor BMS-599626 inhibits tumor cell proliferation and has the potential to increase tumor response to radiotherapy. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
