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    BMS-599626 2HCL(714971-09-2 Free base)

    BMS-599626 2HCL(714971-09-2 Free base)

    Catalog Number: orb1737829

    DispatchUsually dispatched within 3-5 working days
    $ 1,100.00
    Catalog Numberorb1737829
    CategorySmall Molecules
    DescriptionBMS-599626 2HCL(714971-09-2 Free base)
    CAS Number1781932-33-9
    Purity0.9873
    MW603.47
    SMILESO=C(OC[C@@H]1COCCN1)NC2=CN3C(C(NC4=CC=C(N(N=C5)CC6=CC(F)=CC=C6)C5=C4)=NC=N3)=C2C.Cl.Cl
    FormulaC27H29Cl2FN8O3
    Biological ActivityBMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative. BMS-599626 is an orally available and selective dual inhibitor of HER1 and HER2 with IC50s of 20 and 30 nM, respectively. BMS-599626 inhibits tumor cell proliferation and has the potential to increase tumor BMS-599626 inhibits tumor cell proliferation and has the potential to increase tumor response to radiotherapy.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
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