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Catalog Number | orb1301823 |
---|---|
Category | Small Molecules |
Description | BMS 599626 2HCl (873837-23-1(HCl)) |
CAS Number | 1781932-33-9 |
Purity | 99.94% |
MW | 603.48 |
SMILES | O=C(OC[C@@H]1COCCN1)NC2=CN3C(C(NC4=CC=C(N(N=C5)CC6=CC(F)=CC=C6)C5=C4)=NC=N3)=C2C.Cl.Cl |
Formula | C27H29FN8O3Cl2 |
Biological Activity | BMS-599626 (AC480) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, > 100-fold to Lck, VEGFR2, c-Kit, MET, etc. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |