BMS-1166 hydrochloride

• Catalog Number: orb1707540
• Category: Small Molecules
• Description: BMS-1166 hydrochloride
• CAS Number: 2113650-05-6
• Purity: 98%
• MW: 677.57
• SMILES: C(C1=C(OCC2=CC(C#N)=CC=C2)C=C(OCC3=C(C)C(=CC=C3)C=4C=C5C(=CC4)OCCO5)C(Cl)=C1)N6[C@@H](C(O)=O)C[C@@H](O)C6.Cl
• Formula: C₃₆H₃₄Cl₂N₂O₇
• Biological Activity: Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.