BMS-1001 hydrochloride

• Catalog Number: orb1309920
• Category: Small Molecules
• Description: BMS-1001 hydrochloride
• CAS Number: 2113650-04-5
• Purity: 99.57%
• MW: 631.11
• SMILES: Cl.Cc1cc(CN[C@H](CO)C(O)=O)c(OCc2cccc(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1
• Formula: C₃₅H₃₅ClN₂O₇
• Biological Activity: BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.