BL-1249

• Catalog Number: orb1089708
• Category: Small Molecules
• Description: BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM). BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively
• CAS Number: [18200-13-0]
• MW: 291.3503826
• SMILES: N1N=NC(C2=CC=CC=C2NC2=CC=CC3CCCCC2=3)=N1
• Formula: C₁₇H₁₇N₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.