BIX02188 (BIX 02188)

• Catalog Number: orb154720
• Category: Small Molecules
• Description: BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
• CAS Number: [334949-59-6]
• MW: 412.48366
• SMILES: O=C(N)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1
• Formula: C₂₅H₂₄N₄O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of BIX02188 (BIX 02188)