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Catalog Number | orb1692441 |
---|---|
Category | Small Molecules |
Description | 17-phenyl trinor Prostaglandin F2α methyl ester |
CAS Number | 38315-47-8 |
Purity | 98% |
MW | 402.531 |
SMILES | COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCc1ccccc1 |
Formula | C24H34O5 |
Biological Activity | Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |