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Bimatoprost methyl ester

Bimatoprost methyl ester

Catalog Number: orb1692441

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Catalog Numberorb1692441
CategorySmall Molecules
Description17-phenyl trinor Prostaglandin F2α methyl ester
CAS Number38315-47-8
Purity98%
MW402.531
SMILESCOC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCc1ccccc1
FormulaC24H34O5
Biological ActivityProstaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.