Bicuculline methochloride

SKU: orb1983202

Description

Bicuculline methochloride is a convulsant alkaloid and a selective GABAA receptor antagonist (IC50 = 3 μM) that can block Ca²⁺-activated potassium channels. It induces clonic-tonic seizures in mammals and is commonly used to establish animal models of epilepsy.

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Key Properties

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CAS Number	38641-83-7
MW	417.84
Formula	C₂₁H₂₀ClNO₆
SMILES	[Cl-].[H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@]1([H])c2cc3OCOc3cc2CC[N+]1(C)C
Target	Others

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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