Bicuculline methochloride

• Catalog Number: orb1983202
• Category: Small Molecules
• Description: Bicuculline methochloride
• CAS Number: 38641-83-7
• MW: 417.84
• SMILES: [Cl-].[H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@]1([H])c2cc3OCOc3cc2CC[N+]1(C)C
• Formula: C₂₁H₂₀ClNO₆
• Biological Activity: Bicuculline methochloride ((+)-Bicuculline; d-Bicuculline), a selective GABAA receptor antagonist, exhibits an IC50 of 3 μM. It induces tonic-clonic convulsions in mammals and blocks Ca2+ activated potassium channels, making it useful for studying epilepsy and related psychiatric disorders [1] [2].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.