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Catalog Number | orb1680280 |
---|---|
Category | Small Molecules |
Description | Biatractylolide |
CAS Number | 182426-37-5 |
Purity | 98% |
MW | 462.63 |
SMILES | [H][C@]12CC3=C(C)C(=O)OC3(C[C@]1(C)CCCC2=C)[C@@]12C[C@]3(C)CCCC(=C)[C@@]3([H])CC1=C(C)C(=O)O2 |c:3,t:35| |
Formula | C30H38O4 |
Biological Activity | Biatractylolide has a neuroprotective effect on glutamate-induced injury in PC12 and SH-SY5Y cells through a mechanism of the PI3K-Akt-GSK3β-dependent pathways. The molecular mechanisms of inhibitory activities of biatractylolide on AChE are not only through binding to AChE, but also via reducing AChE expression by inhibiting the activity of GSK3β. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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