BI-882370

• Catalog Number: orb1296244
• Category: Small Molecules
• Description: BI-882370
• CAS Number: 1392429-79-6
• Purity: 99.07%
• MW: 569.67
• SMILES: FC1=C(N2C=3C(C(=C2)C=4C=NC=NC4)=NC(N(C)C5CCN(CC)CC5)=CC3)C(F)=CC=C1NS(CCC)(=O)=O
• Formula: C₂₈H₃₃F₂N₇O₂S
• Biological Activity: BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.