BI-671800

• Catalog Number: orb1308569
• Category: Small Molecules
• Description: BI-671800
• CAS Number: 1093108-50-9
• Purity: 98.06%
• MW: 501.5
• SMILES: CN(C)c1nc(Cc(cc2)ccc2NC(c2ccc(C(F)(F)F)cc2)=O)nc(N(C)C)c1CC(O)=O
• Formula: C₂₅H₂₆F₃N₅O₃
• Biological Activity: BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.