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BI-671800
Catalog Number: orb1308569
| Catalog Number | orb1308569 |
|---|---|
| Category | Small Molecules |
| Description | BI-671800 |
| CAS Number | 1093108-50-9 |
| Purity | 99.19% |
| MW | 501.5 |
| SMILES | CN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(O)=O |
| Formula | C25H26F3N5O3 |
| Biological Activity | BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
