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Catalog Number | orb757692 |
---|---|
Category | Small Molecules |
Description | BI-3406 (compound I-6) is a potent, selective and orally active inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with IC50 of 6 nM. BI-3406 reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 exhib |
CAS Number | [2230836-55-0] |
MW | 462.46 |
SMILES | CC1=NC2=CC(=C(C=C2C(=N1)NC(C)C3=CC(=CC(=C3)N)C(F)(F)F)OC4CCOC4)OC |
Formula | C23H25F3N4O3 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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