BI-1467335 HCl

• Catalog Number: orb692041
• Category: Small Molecules
• Description: BI 1467335 (PXS-4728A, PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM; displays > 500-fold selective for VAP-1/SSAO over all the related human amine oxidases; diminishes leukocyte rolling and adherence induced by CXCL1/KC, also inhibits the migration of neutrophils to the lungs in response to LPS, Klebsiella pneumoniae lung infection and CLP induced sepsis.
• CAS Number: [1478364-68-9]
• MW: 316.8
• SMILES: Cl.NC/C(/COC1=CC=C(C(NC(C)(C)C)=O)C=C1)=C\F
• Formula: C₁₅H₂₁FN₂O₂.HCl
• Note: For research use only
• Expiration Date: 12 months from date of receipt.