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Catalog Number | orb134383 |
---|---|
Category | Small Molecules |
Description | Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 > 10000 nM)[1][2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma. |
CAS Number | [153559-49-0] |
MW | 348.4779 |
SMILES | O([H])C(C1C([H])=C([H])C(=C([H])C=1[H])C(=C([H])[H])C1C(C([H])([H])[H])=C([H])C2=C(C=1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])=O |
Formula | C24H28O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of Bexarotene