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Betrixaban
Catalog Number: orb1690000
| Catalog Number | orb1690000 |
|---|---|
| Category | Small Molecules |
| Description | Betrixaban |
| CAS Number | 330942-05-7 |
| Purity | 99.35% |
| MW | 451.91 |
| SMILES | N(C(=O)C1=CC=C(C(N(C)C)=N)C=C1)C2=C(C(NC3=CC=C(Cl)C=N3)=O)C=C(OC)C=C2 |
| Formula | C23H22ClN5O3 |
| Biological Activity | Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [4]. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Betrixaban [orb181210]
[330942-05-7]
451.90548
C23H22N5O3CL
10 mM * 1 mL in DMSO, 100 mg, 1000 mg, 250 mg Betrixaban maleate [orb1221263]
> 98% (HPLC)
936539-80-9
5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mgBetrixaban maleate [orb1302397]
98.81%
936539-80-9
567.98
C27H26ClN5O7
500 mg, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mgBetrixaban hydrochloride(330942-05-7(free base)) [orb1302649]
99.54%
488.36
C23H23Cl2N5O3
2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 5 mg, 1 mg, 1 mL*10mM (in DMSO)
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