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Betrixaban
Catalog Number: orb1690000
| Catalog Number | orb1690000 |
|---|---|
| Category | Small Molecules |
| Description | Betrixaban |
| CAS Number | 330942-05-7 |
| Purity | 99.35% |
| MW | 451.91 |
| SMILES | COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 |
| Formula | C23H22ClN5O3 |
| Biological Activity | Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [4]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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Betrixaban [orb181210]
[330942-05-7]
451.90548
C23H22N5O3CL
1 ml x 10 mm (in DMSO), 100 mg, 1 g, 250 mg Betrixaban maleate [orb1302397]
99.86%
936539-80-9
567.98
C27H26ClN5O7
2 mg, 200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mgBetrixaban hydrochloride(330942-05-7(free base)) [orb1302649]
99.54%
488.36
C23H23Cl2N5O3
2 mg, 10 mg, 25 mg, 50 mg, 5 mg, 100 mg, 1 mg, 1 ml x 10 mm (in DMSO)
