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Catalog Number | orb699504 |
---|---|
Category | Antibodies |
Description | BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14 translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level. |
Species/Host | Mouse |
Clonality | Recombinant |
Clone Number | rBL10/411 |
Tested applications | FACS, IHC-P |
Reactivity | Human |
Isotype | Mouse IgG1, kappa |
Immunogen | Amino acids 122-168 from the human protein were used as the immunogen for the BCL10 antibody. |
Dilution range | Flow cytometry: 1-2ug/million cells,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT |
Purity | Protein G affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This BCL10 antibody is available for research use only. |
UniProt ID | O95999 |
Storage | Store the BCL10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide |
Note | For research use only |
Application notes | Optimal dilution of the BCL10 antibody should be determined by the researcher. |
Expiration Date | 12 months from date of receipt. |
Flow cytometry testing of PFA-fixed human K562 cells with BCL10 antibody (clone rBL10/411); Red=isotype control, Blue= BCL10 antibody.
SDS-PAGE analysis of purified, BSA-free BCL10 antibody (clone rBL10/411) as confirmation of integrity and purity.
ELISA, IF, IHC | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |
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