BCL-XL-IN-3

• Catalog Number: orb2814311
• Category: Small Molecules
• Description: BCL-XL-IN-3 (Compound 11) is an inhibitor of BCL-XL, with a Ki of less than 0.01 nM. It suppresses cell viability in both normal Molt-4 cells and digitonin-permeabilized Molt-4 cells, with EC50 values of 77.8 nM and 0.07 nM, respectively. BCL-XL-IN-3 can be utilized as an ADC toxin for synthesizing Clezutoclax.
• CAS Number: 1949840-87-2
• MW: 834.04
• SMILES: C(C12CC3(OCCNCC[C@@H](CO)O)CC(C)(C1)CC(C)(C2)C3)N4C(C)=C(C=N4)C5=C(C(O)=O)N=C(C=C5)N6CC7=C(C(NC8=NC=9C(S8)=CC=CC9)=O)C=CC=C7CC6
• Formula: C₄₆H₅₅N₇O₆S
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.