BChE-IN-20

• Catalog Number: orb1941854
• Category: Small Molecules
• Description: BChE-IN-20 (compound 7c) is a potent and selective inhibitor of BChE, with IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 μM. BChE-IN-20 serves as a promising template for the design and development of pharmaceutical BChE-selective ligands, including inhibitors and fluorogenic probes.
• CAS Number: 1428439-79-5
• Purity: 98.00%
• MW: 465.63
• SMILES: O=C(OC)C1=CN(CCC=2N=C(N=C(NCCCN(CC)CC)C2C1)C=3C=CC=CC3)C(C)C
• Formula: C₂₇H₃₉N₅O₂
• Biological Activity: BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 μM. As a promising template, BChE-IN-20 advances the design and development of pharmaceutical BChE-selective ligands, encompassing inhibitors and fluorogenic probes.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.